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个人信息Personal Information
教授
博士生导师
硕士生导师
性别：女
毕业院校：大连理工大学
学位：博士
所在单位：生物工程学院
学科：生物化工. 生物工程与技术. 药物工程
办公地点：生物楼512
联系方式：wangjingyun67@dlut.edu.cn
电子邮箱：wangjingyun67@dlut.edu.cn
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A Nile blue based infrared fluorescent probe: imaging tumors that over-express cyclooxygenase-2
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论文类型：期刊论文
发表时间：2015-01-14
发表刊物：CHEMICAL COMMUNICATIONS
收录刊物：SCIE、PubMed、Scopus
卷号：51
期号：4
页面范围：792-795
ISSN号：1359-7345
摘要：The first Golgi-localized cyclooxygenase-2 (COX-2)-specific near-infrared (NIR) fluorescent probe, Niblue-C6-IMC, able to detect cancer cells, was designed. Importantly, Niblue-C6-IMC preferentially labeled the tumors in a mouse tumor model with deep tissue penetration capacity. It may be a promising molecular tool for guiding tumor resection during surgery.