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论文类型：期刊论文

发表时间：2014-07-01

发表刊物：SCIENCE CHINA-CHEMISTRY

收录刊物：SCIE、EI

卷号：57

期号：7

页面范围：1043-1047

ISSN号：1674-7291

关键字：turn-on; gold ion fluorescent probe; low detection limit; good selectivity and sensitivity; bioimaging application

摘要：A new fluorescent probe RY was synthesized for the detection of Au3+ ions based on a rhodamine B derivative. The fluorescent probe showed good selectivity and sensitivity to Au3+ ions. Obvious color and fluorescence changes could be observed with the naked eye while the fluorescent probe reacted with the Au3+ ions. The detection limit of the probe was determined to be 36 ppb by the fluorescence titration; the excellent linear relationship suggests that the probe is potentially useful for quantitative detection of Au3+ in vitro. We also demonstrated its bioimaging application in both living cells and mice; this was the first time that a fluorescent probe was successfully applied to imaging Au3+ in living animals.