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个人信息Personal Information
教授
博士生导师
硕士生导师
性别：女
毕业院校：大连理工大学
学位：博士
所在单位：生物工程学院
学科：生物化工. 生物工程与技术. 药物工程
办公地点：生物楼512
联系方式：wangjingyun67@dlut.edu.cn
电子邮箱：wangjingyun67@dlut.edu.cn
A Heterodinuclear Complex OsIr Exhibiting Near-Infrared Dual Luminescence Lights Up the Nucleoli of Living Cells
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论文类型：期刊论文
发表时间：2014-06-09
发表刊物：ORGANOMETALLICS
收录刊物：SCIE、EI、Scopus
卷号：33
期号：11
页面范围：2681-2684
ISSN号：0276-7333
摘要：The heterodinuclear metal complex OsIr has been designed and synthesized. Upon irradiation with visible light, OsIr exhibits dual luminescence (534 and 721 nm) due to the coexistence of the iridium and osmium activating centers. The cellular uptake of OsIr examined by laser scanning confocal microscopy revealed an apparent nucleolar staining. The iridium moiety interacts with proteins and RNA to trigger a significant luminescence enhancement, whereas the osmium moiety displays a near-infrared luminescence; a ratiometric luminescence response between the two moieties was observed upon protein addition.